Prognostic value of duration of untreated psychosis in long-term outcome of schizophrenia

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چکیده

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Prognostic value of duration of untreated psychosis in long-term outcome of schizophrenia

BACKGROUND The goal of this prognostic study was to investigate whether the duration of untreated psychosis (DUP) may have a prognostic value with regard to the further course of the illness. MATERIAL/METHODS Fifty-eight patients (77% of the original study group) diagnosed with DSM III schizophrenia and later re-diagnosed with DSM IV T-R were assessed at 4 time points. Number of relapses, ave...

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Influence of duration of untreated psychosis on the short-term outcome of drug-free schizophrenia patients

Western studies in the recent past have suggested that reducing the duration of untreated psychosis (DUP) is associated with better control of symptoms of schizophrenia. The present investigation attempts to assess the influence of duration of untreated psychosis and other predictors on the outcome of schizophrenia, six weeks after the treatment. Data of 45 DSM-IV schizophrenia patients (Mean a...

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Duration of untreated psychosis as predictor of long-term outcome in schizophrenia: systematic review and meta-analysis.

BACKGROUND Duration of untreated psychosis (DUP) is one of the few potentially modifiable predictors of outcomes of schizophrenia. Long DUP as a predictor of poor short-term outcome has been addressed in previous meta-analyses, but the long-term effects of DUP remain unclear. AIMS To analyse the associations between DUP and long-term outcomes of schizophrenia. METHOD A systematic literature...

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Effects of duration of untreated psychosis on long-term outcome of people hospitalized with first episode schizophrenia

Duration of untreated psychosis (DUP) has emerged as a reliable predictor of outcome but continues to remain under scientific scrutiny. The present study examines the effect of differential periods of DUP on long-term outcome of first episode schizophrenia at Mumbai, India. This research was a prospective, 10-year follow-up naturalistic study. Hospitalized patients of first episode schizophreni...

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Duration of untreated psychosis and the long-term course of schizophrenia.

This study examines the relationship between duration of untreated psychosis (DUP) and long-term symptomatic and social outcome in 205 patients with schizophrenia, whose parents are member of a consumer organisation. We found only a tendency that longer DUP was related to negative symptoms, but no relation to other outcome domains. The results of this study do not support antipsychotic interven...

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ژورنال

عنوان ژورنال: Medical Science Monitor

سال: 2011

ISSN: 1234-1010

DOI: 10.12659/msm.881768